Ann Patchett and the late Lucy Grealy met in college in 1981, and, after enrolling in the Iowa Writers’ Workshop, began a friendship that would be as defining to both of their lives as their work.

In Grealy’s critically acclaimed memoir, Autobiography of a Face, she wrote about losing part of her jaw to childhood cancer, years of chemotherapy and radiation, and endless reconstructive surgeries. In Truth & Beauty, the story isn’t Lucy’s life or Ann’s life, but the parts of their lives they shared.

This is a portrait of unwavering commitment that spans twenty years, from the long winters of the Midwest, to surgical wards, to book parties in New York. Through love, fame, drugs, and despair, this is what it means to be part of two lives that are intertwined... and what happens when one is left behind.

This is a tender, brutal book about loving the person we cannot save. It is about loyalty, and being lifted up by the sheer effervescence of someone who knew how to live life to the fullest.

From Anne Lamott, the New York Times-bestselling author of Help, Thanks, Wow, comes the book we need from her now: How to bring hope back into our lives.

"I am stockpiling antibiotics for the Apocalypse, even as I await the blossoming of paperwhites on the windowsill in the kitchen," Anne Lamott admits at the beginning of Almost Everything. Despair and uncertainty surround us: in the news, in our families, and in ourselves. But even when life is at its bleakest--when we are, as she puts it, "doomed, stunned, exhausted, and over-caffeinated"--the seeds of rejuvenation are at hand. "All truth is paradox," Lamott writes, "and this turns out to be a reason for hope. If you arrive at a place in life that is miserable, it will change." That is the time when we must pledge not to give up but "to do what Wendell Berry wrote: 'Be joyful, though you have considered all the facts.'"

In this profound and funny book, Lamott calls for each of us to rediscover the nuggets of hope and wisdom that are buried within us that can make life sweeter than we ever imagined. Divided into short chapters that explore life's essential truths, Almost Everything pinpoints these moments of insight as it shines an encouraging light forward.

Anne Lamott explores the concept of mercy in her enthralling and heartening book, Hallelujah Anyway: Rediscovering Mercy. She delves into the idea that mercy is radical kindness. It's the permission you give others—and yourself—to forgive a debt, to absolve the unabsolvable, to let go of the judgment and pain that make life so difficult.

In this profound and caring book, Lamott ventures to explore where to find meaning in life. She suggests we begin by facing a great big mess, especially the great big mess of ourselves. It's up to each of us to recognize the presence and importance of mercy everywhere—within us and outside us, all around us—and to use it to forge a deeper understanding of ourselves and more honest connections with each other.

While that can be difficult to do, Lamott argues that it's crucial, as kindness towards others, beginning with myself, buys us a shot at a warm and generous heart, the greatest prize of all. Full of Lamott’s trademark honesty, humor, and forthrightness, Hallelujah Anyway is a hopeful book of hands-on spirituality.

A powerful and inspiring examination of the connection between the potential for great talent and conditions commonly thought to be “disabilities,” revealing how the source of our struggles can be the origin of our greatest strengths.

In The Power of Different, psychiatrist and bestselling author Gail Saltz examines the latest scientific discoveries, profiles famous geniuses who have been diagnosed with all manner of brain “problems”—including learning disabilities, ADD, anxiety, Depression, Bipolar disorder, schizophrenia, and Autism—and tells the stories of lay individuals to demonstrate how specific deficits in certain areas of the brain are directly associated with the potential for great talent.

Saltz shows how the very conditions that cause people to experience difficulty at school, in social situations, at home, or at work, are inextricably bound to creative, disciplinary, artistic, empathetic, and cognitive abilities.

In this pioneering work, readers will find engaging scientific research and stories from historical geniuses and everyday individuals who have not only made the most of their conditions, but who have flourished because of them. They are leaning into their brain differences to:

• Identify areas of interest and expertise
• Develop work arounds
• Create the environments that best foster their talents
• Forge rewarding interpersonal relationships

Enlightening and inspiring, The Power of Different proves that the unique wiring of every brain can be a source of strength and productivity, and contributes to the richness of our world.

More American women are childless than ever before—nearly half those of childbearing age don’t have children. While our society often assumes these women are “childfree by choice,” that’s not always true. In reality, many of them expected to marry and have children, but it simply hasn’t happened. Wrongly judged as picky or career-obsessed, they make up the “Otherhood,” a growing demographic that has gone without definition or visibility until now.

In Otherhood, author Melanie Notkin reveals her own story as well as the honest, poignant, humorous, and occasionally heartbreaking stories of women in her generation—women who expected love, marriage, and parenthood, but instead found themselves facing a different reality. She addresses the reasons for this shift, the social and emotional impact it has on our collective culture, and how the “new normal” will affect our society in the decades to come.

Notkin aims to reassure women that they are not alone and encourages them to find happiness and fulfillment no matter what the future holds. A groundbreaking exploration of an essential contemporary issue, Otherhood inspires thought-provoking conversation and gets at the heart of our cultural assumptions about single women and childlessness.

The Emperor of All Maladies is a magnificent, profoundly humane biography of cancer - from its first documented appearances thousands of years ago through the epic battles in the twentieth century to cure, control, and conquer it to a radical new understanding of its essence.

Physician, researcher, and award-winning science writer, Siddhartha Mukherjee examines cancer with a cellular biologist’s precision, a historian’s perspective, and a biographer’s passion. The result is an astonishingly lucid and eloquent chronicle of a disease humans have lived with - and perished from - for more than five thousand years.

The story of cancer is a story of human ingenuity, resilience, and perseverance, but also of hubris, paternalism, and misperception. Mukherjee recounts centuries of discoveries, setbacks, victories, and deaths, told through the eyes of his predecessors and peers, training their wits against an infinitely resourceful adversary that, just three decades ago, was thought to be easily vanquished in an all-out “war against cancer.”

The book reads like a literary thriller with cancer as the protagonist. From the Persian Queen Atossa, whose Greek slave cut off her malignant breast, to the nineteenth-century recipients of primitive radiation and chemotherapy to Mukherjee’s own leukemia patient, Carla, The Emperor of All Maladies is about the people who have soldiered through fiercely demanding regimens in order to survive—and to increase our understanding of this iconic disease.

Riveting, urgent, and surprising, The Emperor of All Maladies provides a fascinating glimpse into the future of cancer treatments. It is an illuminating book that provides hope and clarity to those seeking to demystify cancer.

One of today’s most admired and controversial political figures, Ayaan Hirsi Ali burst into international headlines following the murder of Theo van Gogh by an Islamist who threatened that she would be next. She made headlines again when she was stripped of her citizenship and resigned from the Dutch Parliament.

Infidel shows the coming of age of this distinguished political superstar and champion of free speech as well as the development of her beliefs, iron will, and extraordinary determination to fight injustice. Raised in a strict Muslim family, Hirsi Ali survived civil war, female mutilation, brutal beatings, adolescence as a devout believer during the rise of the Muslim Brotherhood, and life in four troubled, unstable countries ruled largely by despots. She escaped from a forced marriage and sought asylum in the Netherlands, where she earned a college degree in political science, tried to help her tragically depressed sister adjust to the West, and fought for the rights of Muslim women and the reform of Islam as a member of Parliament. Under constant threat, demonized by reactionary Islamists and politicians, disowned by her father, and expelled from family and clan, she refuses to be silenced.

Ultimately a celebration of triumph over adversity, Hirsi Ali’s story tells how a bright little girl evolves out of dutiful obedience to become an outspoken, pioneering freedom fighter. As Western governments struggle to balance democratic ideals with religious pressures, no other book could be more timely or more significant.

At the center of Mountains Beyond Mountains stands Paul Farmer. Doctor, Harvard professor, renowned infectious-disease specialist, anthropologist, the recipient of a MacArthur "genius" grant, world-class Robin Hood, Farmer was brought up in a bus and on a boat, and in medical school found his life’s calling: to diagnose and cure infectious diseases and to bring the lifesaving tools of modern medicine to those who need them most.

Mountains Beyond Mountains takes us from Harvard to Haiti, Peru, Cuba, and Russia as Farmer changes minds and practices through his dedication to the philosophy that "the only real nation is humanity"—a philosophy that is embodied in the small public charity he founded, Partners in Health. He enlists the help of the Gates Foundation, George Soros, the U.N.’s World Health Organization, and others in his quest to cure the world.

At the heart of this book is the example of a life based on hope, and on an understanding of the truth of the Haitian proverb "Beyond mountains there are mountains": as you solve one problem, another problem presents itself, and so you go on and try to solve that one too.

In a small neighborhood, atop a hill in Pittsburgh, thrives a world where neighbors don't move away, where friends become family, and where community takes on a deeper meaning. Welcome to the inviting and intriguing neighborhood of Troy Hill. Unlike nearby towns, the families of Troy Hill have lived in the same neighborhood for generations, providing continuity in these women's lives and depth in their relationships. They christened babies, raised children, and even buried their loved ones together. Now in their seventies and eighties, the women of Troy Hill form a community of independent souls, who find joy in each other and solace in service.

Troy Hill and these women resonate beyond this hilltop, providing insight into bonds between mothers and daughters, husbands and wives, sisters and friends. From them we learn to shape our lives with love and humor.

Veteran reporter Clare Ansberry brings to life these vibrant women, and offers some invaluable lessons about acceptance, faith, and family. A portrait of American life and a hymn to the durability of the human spirit, The Women of Troy Hill is an inspiration for us all.

On a hilltop north of Seattle, overlooking the glorious vista of Puget Sound and the white-capped Olympics, stands Rosary Heights, the motherhouse of the Sisters of Saint Dominic of the Holy Cross. The story begins here, with a catastrophic storm that shifts the ground beneath the motherhouse and threatens to send it crashing into the waters below. In a single act of nature, a moment of truth, the order is forced to rethink its place in the world and its purpose.

With Rosary Heights as the backdrop, Catherine Whitney takes a personal journey inside the order that ran the school she attended as a child, the order that, for a short time, she contemplated entering herself. Her quest is to come to terms with what it means to be called to the religious life. What is the secret these women hold that makes them--no matter how diverse--perform common rituals, celebrate the same Mass, and serve the same God?

In The Calling, we meet several valiant women who struggle with the practicalities of the world around them as well as the complicating issues of the life of a nun. Each woman's story is compelling. Together, they form a dramatic human chronicle that is fascinating and revealing--a chronicle of a community that has existed for centuries but is still evolving and whose anxieties and joys are utterly relevant to all of us, regardless of our beliefs.