The conclusion of the Phantom Blood Arc! Jonathan Joestar and his mentor Zeppelli continue their pursuit of the villainous vampire, Dio! But to get to him, they must first face down his murderous henchmen! In battle after bloody battle, JoJo and Zeppelli are pushed to their limits and beyond!

As if Dio wasn't diabolical enough, now he's an immortal vampire with incredible strength! But Jonathan Joestar's not one to back down, even when it seems like victory is impossible! It's a classic battle! Good versus evil! Grit and determination against power and arrogance! Who will win?!

Young Jonathan Joestar's life is forever changed when he meets his new adopted brother, Dio. For some reason, Dio has a smoldering grudge against him and derives pleasure from seeing him suffer. But every man has his limits, as Dio finds out. This is the beginning of a long and hateful relationship!