From former CEO and popular TED speaker Margaret Heffernan comes a timely and enlightening book that equips you with the tools you need to face the future with confidence and courage.

How can we think about the future? What do we need to do—and who do we need to be? In her bold and invigorating new book, distinguished businesswoman and author Margaret Heffernan explores the people and organizations who aren't daunted by uncertainty. We are addicted to prediction, desperate for certainty about the future. But the complexity of modern life won't provide that; experts in forecasting are reluctant to look more than 400 days out. History doesn't repeat itself and even genetics won't tell you everything you want to know. Tomorrow remains uncharted territory, but Heffernan demonstrates how we can forge ahead with agility.

Drawing on a wide array of people and places, Uncharted traces long-term projects that shrewdly evolved over generations to meet the unpredictable challenges of every new age. Heffernan also looks at radical exercises and experiments that redefined standard practices by embracing different perspectives and testing fresh approaches. Preparing to confront a variable future provides the antidote to passivity and prediction. Ranging freely through history and from business to science, government to friendships, this refreshing book challenges us to mine our own creativity and humanity for the capacity to create the futures we want and can believe in.

Hidden Valley Road: Inside the Mind of an American Family unfolds the heartrending story of a mid-century American family with twelve children, six of them diagnosed with schizophrenia, that became science's great hope in the quest to understand—even cure—the disease.

Don and Mimi Galvin seemed to be living the dream. After World War II, Don's work with the US Air Force brought them to Colorado, where their twelve children perfectly spanned the baby boom: the oldest born in 1945, the youngest in 1965. In those years there was an established script for a family like the Galvins—aspiration, hard work, upward mobility, domestic harmony—and they worked hard to play their parts. But behind the scenes was a different story: psychological breakdown, sudden shocking violence, hidden abuse.

By the mid-1970s, six of the ten Galvin boys were diagnosed as schizophrenic. How could all this happen in one family? What took place inside the house on Hidden Valley Road was so extraordinary that the Galvins became one of the first families to be studied by the National Institutes of Mental Health.

Their shocking story also offers a shadow history of the science of schizophrenia, from the era of institutionalization, lobotomy and the premise of the schizophrenogenic mother, to the search for genetic markers for the disease, always amidst profound disagreements about the nature of the illness itself. Unknown to the Galvins, samples of their DNA informed decades of genetic research that continues today, offering paths to treatment and even the possibility of the eradication of the disease for future generations.

With clarity and compassion, bestselling and award-winning author Robert Kolker uncovers one family's unforgettable legacy of suffering, love and hope.