"Oscar et la dame rose" presents the letters sent to God by a ten-year-old child. These letters were discovered by Mamie Rose, the "dame rose" who visits him at the children's hospital. They describe twelve days in the life of Oscar, twelve days that are quirky and poetic, filled with funny and moving characters. These twelve days might be his last twelve. However, thanks to the strong bond of love formed with Mamie Rose, these twelve days will become legendary.

If a man has lost a leg or an eye, he knows he has lost a leg or an eye; but if he has lost a self—himself—he cannot know it, because he is no longer there to know it. Dr. Oliver Sacks recounts the stories of patients struggling to adapt to often bizarre worlds of neurological disorder. Here are people who can no longer recognize everyday objects or those they love; who are stricken with violent tics or shout involuntary obscenities; who have been dismissed as autistic or retarded, yet are gifted with uncanny artistic or mathematical talents. If inconceivably strange, these brilliant tales illuminate what it means to be human.