In this father-son collaboration, Stephen King and Owen King tell the story of what might happen if women disappeared from the world of men. Set in a small Appalachian town whose primary employer is a women's prison, in a future so real and near it might be now, something happens when women go to sleep. They become shrouded in a cocoon-like gauze. If they are awakened, if the gauze wrapping their bodies is disturbed or violated, the women become feral and spectacularly violent. While they sleep they go to another place.

The men of our world are abandoned, left to their increasingly primal devices. One woman, however, the mysterious Evie, is immune to the blessing or curse of the sleeping disease. Is Evie a medical anomaly to be studied, or is she a demon who must be slain?