The Little Giant of Aberdeen County is a captivating multi-generational tale with dark aspects and a touch of witchcraft. It tells the story of Truly, a girl grown massive due to a pituitary problem, who finds her calling and a future that no one expected.

When Truly Plaice's mother was pregnant, the town of Aberdeen joined together in betting on how record-breakingly huge the baby boy would be. The girl who turned out to be Truly paid the price of her enormity; her father blamed her for her mother's death in childbirth and was ill-equipped to raise either this giant child or her polar opposite sister, Serena Jane.

Separated after her father's death, Serena Jane lives a life of privilege, while Truly lives on the outskirts of town, enduring constant abuse. Serena Jane's beauty becomes both a blessing and a curse, leading to an obsession by Bob Bob Morgan, a classmate from a line of doctors. The town's history is intertwined with witchcraft, as the earliest Robert Morgan married the town witch, Tabitha Dyerson.

When Serena Jane flees a loveless marriage, Truly must become the woman of an unwanted house and mother to her nephew. Her brother-in-law is relentless in his cruelty, but Truly's discovery of her ability to heal with herbs offers her a path to regain control over her life.

Unearthed family secrets lead to betrayals that threaten to break the Morgan family apart forever. However, Truly's reckoning with her own demons allows for an uprooting of Aberdeen County and the possibility of love in unexpected places.