Spanning the period between the Chicago World's Fair of 1893 and the years just after World War I, this novel moves from the labor troubles in Colorado to turn-of-the-century New York, to London and Gottingen, Venice and Vienna, the Balkans, Central Asia, and Siberia at the time of the mysterious Tunguska Event. It also covers Mexico during the Revolution, postwar Paris, silent-era Hollywood, and one or two places not strictly speaking on the map at all.

With a worldwide disaster looming just a few years ahead, it is a time of unrestrained corporate greed, false religiosity, and evil intent in high places. The sizable cast of characters includes anarchists, balloonists, gamblers, corporate tycoons, drug enthusiasts, innocents and decadents, mathematicians, mad scientists, shamans, psychics, stage magicians, spies, detectives, adventuresses, and hired guns. There are cameo appearances by historical figures such as Nikola Tesla, Bela Lugosi, and Groucho Marx.

As an era of certainty comes crashing down around their ears and an unpredictable future commences, these folks are mostly just trying to pursue their lives. Sometimes they manage to catch up; sometimes it's their lives that pursue them.