Jennifer Ann Kirkman is an American stand-up comedian, screenwriter, podcaster, and actress. She is well known for her regular appearances as a round-table panelist on Chelsea Lately for 70 episodes from 2008 to 2014.

Jen Kirkman has also been a guest on @midnight, as well as known for her appearances on the Funny or Die sketch series Drunk History and its continuation television series on Comedy Central.

Her first three comedy albums released are Self Help (2006), Hail to the Freaks (2011), and I'm Gonna Die Alone (And I Feel Fine) (2016), the latter also serving as her debut stand-up feature for Netflix. Her second stand-up feature, Just Keep Livin'?, premiered in January 2017 and was released as an album in November 2018.

Her debut book, I Can Barely Take Care of Myself: Tales From a Happy Life Without Kids, was published in April 2013, and became a New York Times bestseller.