Deborah Smith Howe (August 12, 1946 – June 3, 1978) was an American children's writer and actress, renowned for her collaboration with her husband, James Howe, on the classic children's book Bunnicula: A Rabbit-Tale of Mystery. Born in Boston, Massachusetts, Deborah's early life was steeped in creativity, with her father Lester Smith being a notable radio newscaster in New York. She was raised in Chelsea, Massachusetts, and later pursued her passion for the arts by obtaining a B.F.A. in theater from Boston University in 1968.

It was at college where she met James Howe, a fellow student in the acting program. The couple married on September 28, 1969, and relocated to New York City to chase their acting dreams. Deborah found herself immersed in the world of acting, participating in off-Broadway shows from 1969 to 1978. Besides acting, she also explored other artistic avenues, including modeling and working as a tape recording artist. Alongside her husband, she co-created children's records, showcasing her diverse talents.

In 1978, while battling a terminal bone disease, ameloblastoma, Deborah and James penned Bunnicula and Teddy Bear's Scrapbook during her stay at St. Vincent's Hospital and Medical Center. According to James, writing the books served as a therapeutic escape, offering them moments of laughter and joy amidst the challenges of Deborah's illness. Sadly, she passed away on June 3, 1978, 11 months after her diagnosis, leaving behind a legacy that would enchant young readers for generations. A children's library at St. Vincent's was later named in her honor, memorializing her contributions to children's literature.